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Genes and Proteins

Investigation 2

Investigation 2

Genes and Proteins

Phase 1 – Defined Understanding

Student Guide

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Student Guide with answers

Teacher PreLab

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Phase 2 – Dynamic Understanding

Investigation Two Summary – Lab Goals

In Investigation Two, you analyzed how the sequence of the amino acids in a protein can affect the structure of the protein. During this Investigation, you:

1. Modeled a wild type protein and 4 mutations.

2. Observed the effects of the mutations on the protein structure and function.

3. Calculated the rate of water transfer using the following formula:

 

Investigation Two Summary – Learning Goals

Through these experiments, you concluded that:

1. Mutations in DNA can lead to changes in the amino acid sequence of a protein. Changes in amino acid sequence can cause changes to protein structure. Changes in protein structure may cause changes in function. If a protein cannot function properly, some of the functions of the organism may be affected because the functions of an organism often depend on the functions of the proteins within the organism. However, not all mutations cause changes in an organism. Some mutations in DNA do not cause changes in the amino acid sequence of a protein and therefore do not change a protein’s structure or function. Some mutations in DNA cause changes in amino acid sequences without changing the structure and function of a protein. Some mutations cause changes in the structure of a protein without affecting the function of a protein.

 

Concept Slides

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Mathematics Concepts in This Investigation

  • patterns/sequences
  • grouping
  • data table
  • volume in mL and liters
  • time in seconds
  • calculate the rate of water transfer (ml/s)
  • division
  • calculate averages
  • addition
  • decimals to the nearest tenth
  • greater than/less than/equal to
  • problem-solving
  • comparing values
  • data analysis

Phase 3 – Deeper Understanding

Formative Assessment

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